Effects of 1. 32-micron Nd-YAG laser on brain thermal and histological experimental data

Journal Article · Sat Dec 01 04:00:00 EST 1990 · Surgical Neurology (Tryon, N.C.); (USA)

DOI:https://doi.org/10.1016/0090-3019(90)90244-J· OSTI ID:6317924

Roux, F X; Mordon, S; Fallet-Bianco, C; Merienne, L; Devaux, B C; Chodkiewicz, J P ^[1]

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1. C.H. Sainte-Anne, Paris (France)

Considering that the 1.32-microns Nd-YAG laser should have physicothermal properties close to those of the CO2 laser, a series of experiments were conducted on rat cortex (N = 51). Three laser wavelengths were compared: CO2 laser (10.6 microns), 1.06-microns Nd-YAG, and 1.32-microns Nd-YAG lasers. For each shot, temperature measurements were recorded with an infrared thermographic videocamera. The digitized signals were figured as thermal profiles and temperature developments. Ninety-five shots were correctly studied and analyzed: CO2, N = 29; 1.06-microns Nd-YAG, N = 20; 1.32-microns Nd-YAG, N = 46. The histological lesions produced by these three lasers were compared on animals killed 24 hours (N = 20), 8 days (N = 20), and 30 days (N = 5) after the laser impacts. For equivalent densities of energy, the depth of cortical necrosis was comparable for the CO2 laser (200-250 microns) and the 1.32-microns Nd-YAG laser (210-260 microns) whatever the date of death; the 1.06-microns Nd-YAG laser shots were responsible for much more important damage (400-550 microns). Because of its important absorption in water and nervous tissue, the authors consider the 1.32-microns Nd-YAG laser most suitable for neurosurgery, particularly because it is conducted through optic fibers, and therefore is easy to handle during neurosurgical procedures.

• OSTI ID: 6317924
• Journal Information: Surgical Neurology (Tryon, N.C.); (USA), Journal Name: Surgical Neurology (Tryon, N.C.); (USA) Vol. 34:6; ISSN SGNRA; ISSN 0090-3019
• Country of Publication: United States
• Language: English

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