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Microdosimetry of fast neutrons in selected biological materials

Thesis/Dissertation ·
OSTI ID:6315082
Microdosimetric quantities for selected neutron beams have been determined in muscle, brain, bone, and fat tissue equivalent materials. The quantities of interest were the dose distribution in lineal energy, frequency average lineal energy, dose average lineal energy, and dose average quality factor. A dose response factor was defined to combine the lineal energy dose spectrum with a response function per unit KERMA for an acute biological endpoint in prototype cells in vitro. The dependence of each quantity on material composition and neutron energy was investigated by theoretical calculation and separated into primary and scatter neutron fluence components. Neutron fluences in phantoms were calculated using a standard Monte Carlo code (MCNP). The charged particle fluences and lineal energy dose spectra were obtained using the continuous slowing-down approximation. Calculated microdosimetric spectra agreed with those measured in muscle-equivalent materials. The microdosimetry of primary and scattered neutrons in a large tissue phantom was calculated for three representative uncollimated neutron sources.
Research Organization:
Pennsylvania Univ., Philadelphia (USA)
OSTI ID:
6315082
Country of Publication:
United States
Language:
English

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