CT features of nonfunctioning islet cell carcinoma

Conference · Thu Nov 01 04:00:00 EST 1984 · Am. J. Roentgenol. Radium Ther.; (United States)

OSTI ID:6306544

Eelkema, E A; Stephens, D H; Ward, E M; Sheedy, II, P F

To determine the computed tomographic (CT) characteristics of nonfunctioning islet cell carcinoma of the pancreas, the CT scans of 27 patients with that disease were reviewed. The pancreatic tumor was identified as a mass in 26 patients (96%) Of the 25 tumors evaluated with contrast enhancement, 20 became partially diffusely hyperdense relative to nearby normal pancreatic tissue. Hepatic metastases were identified in 15 patients (56%), regional lymphadenopathy in 10 (37%), atrophy of the gland proximal to the tumor in six (22%), dilatation of the biliary ducts in five (19%), and dilatation of the pancreatic duct in four (15%). The CT appearances of the nonfunctioning islet cell tumors were compared with those of 100 ordinary (ductal) pancreatic adenocarcinomas. Although the two types of tumors were sometimes indistinguishable, features found to be more characteristic of islet cell carcinoma included a pancreatic mass of unusually large size, calcification within the tumor, and contrast enhancement of either the primary tumor or hepatic metastases. Involvement of the celiac axis or proximal superior mesenteric artery was limited to ductal carcinoma.

• Research Organization: Mayo Clinic and Mayo Foundation, Rochester, MN
• OSTI ID: 6306544
• Conference Information: Journal Name: Am. J. Roentgenol. Radium Ther.; (United States) Journal Volume: 143:5
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
CALCINOSIS
CARCINOMAS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
GLANDS
LIVER
METASTASES
NEOPLASMS
ORGANS
PANCREAS
PATHOLOGICAL CHANGES
PATIENTS
TOMOGRAPHY