Effects of air pollution on airway function. Final report May 80-May 81
Asthmatic individuals can develop bronchoconstriction on brief exposure to levels of sulfur dioxide (SO2) observed in urban air. In these studies conducted at rest, asthmatics breathing 1 and 3 ppm SO2 developed significant bronchoconstriction; whereas nonasthmatic subjects developed bronchoconstriction only after breathing 5 ppm. Exercise potentiates this response in asthmatics: exposure to SO2 for 10 minutes while performing light to moderate exercise caused bronchospasms at 0.5 and 0.25 ppm. Bronchoconstriction during light exercise caused by SO2 is less with oronasal breathing (facemask) when compared to oral breathing (mouthpiece). At higher levels of exercise the protection of oronasal breathing is lost probably because more air is taken in through the mouth as ventilation increases.
- Research Organization:
- California Univ., San Francisco (USA). School of Medicine
- OSTI ID:
- 6304252
- Report Number(s):
- PB-83-130252
- Country of Publication:
- United States
- Language:
- English
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Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
570000 -- Health & Safety
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
AIR POLLUTION
ASTHMA
CHALCOGENIDES
DISEASES
EPIDEMIOLOGY
HAZARDS
HEALTH HAZARDS
INHALATION
INTAKE
OXIDES
OXYGEN COMPOUNDS
POLLUTION
RESPIRATORY SYSTEM DISEASES
SULFUR COMPOUNDS
SULFUR DIOXIDE
SULFUR OXIDES
URBAN AREAS