Relative flow of blood cells, platelets, and microspheres in outer and inner renal cortex
Journal Article
·
· Am. J. Physiol.; (United States)
OSTI ID:6292050
Blood platelets (Pl) may attain a relatively high marginal concentration in arterioles, perhaps also in arteries. Along a renal interlobular artery, blood passes several successive arterioles, each arteriole receiving a small flow fraction from a narrow zone adjacent to the artery wall. Thus, in theory, the Pl concentration should cumulatively decrease as the blood approaches the outer cortex, contrary to the concentration of red and white blood cells (RBC and WBC). This was tested by assessing the concentrations of these blood elements, and for comparison, the concentrations of 0.3-, 1.8-, and 3.5- m microspheres (MS), in serial blood samples from veins separately draining the outer and inner cortex in cat kidney. The outer-to-inner cortical concentration ratio was 1.28 for WBC, 1.04 for RBC, and 0.75 for Pl, confirming the working hypothesis. The RBC demargination corresponded to that of MS smaller that 1.8 m, the demargination of WBC to that of MS larger than 3.5 m. In contrast to Pl the even smaller 0.3- m MS were not marginated. Thus, the margination of platelets may not be due merely to their small size.
- Research Organization:
- Univ. of Bergen, Norway
- OSTI ID:
- 6292050
- Journal Information:
- Am. J. Physiol.; (United States), Journal Name: Am. J. Physiol.; (United States) Vol. 251:2; ISSN AJPHA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Quantifying Platelet Margination in Diabetic Blood Flow
Countercurrent diffusion in the renal cortex of the rabbit
Predicting dynamics and rheology of blood flow: A comparative study of multiscale and low-dimensional models of red blood cells
Journal Article
·
Mon Oct 01 00:00:00 EDT 2018
· Biophysical Journal
·
OSTI ID:1565723
Countercurrent diffusion in the renal cortex of the rabbit
Journal Article
·
Mon Oct 01 00:00:00 EDT 1984
· Circ. Res.; (United States)
·
OSTI ID:5779125
Predicting dynamics and rheology of blood flow: A comparative study of multiscale and low-dimensional models of red blood cells
Journal Article
·
Fri May 27 00:00:00 EDT 2011
· Microvascular Research, 82(2):163-170
·
OSTI ID:1021828
Related Subjects
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BLOOD FLOW
BLOOD PLATELETS
BLOOD PRESSURE
BODY
BODY FLUIDS
CATS
DAYS LIVING RADIOISOTOPES
DYNAMIC FUNCTION STUDIES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
KIDNEYS
MAMMALS
MATERIALS
MICROSPHERES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHYSIOLOGY
RADIOISOTOPES
STRONTIUM 85
STRONTIUM ISOTOPES
TRACER TECHNIQUES
VERTEBRATES
59 BASIC BIOLOGICAL SCIENCES
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BLOOD FLOW
BLOOD PLATELETS
BLOOD PRESSURE
BODY
BODY FLUIDS
CATS
DAYS LIVING RADIOISOTOPES
DYNAMIC FUNCTION STUDIES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
KIDNEYS
MAMMALS
MATERIALS
MICROSPHERES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHYSIOLOGY
RADIOISOTOPES
STRONTIUM 85
STRONTIUM ISOTOPES
TRACER TECHNIQUES
VERTEBRATES