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Pathway of plasmid transformation in pneumococcus

Conference ·
OSTI ID:6291399
Plasmids transform Streptococcus pneumoniae by a process involving low efficiency assembly of replicons from fragments of single strands that have entered the cell separately. Transformation of preexisting replicons is much more efficient. We have cloned the erm gene of pIP501 into pMV158, which so far as we know is the first example of cloning in a pneumococcus host-vector system.
Research Organization:
Duke Univ., Durham, NC (USA). Dept. of Biochemistry
DOE Contract Number:
AS05-76EV03941
OSTI ID:
6291399
Report Number(s):
DOE/EV/03941-57; CONF-810150-1; ON: DE81025931
Country of Publication:
United States
Language:
English

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