Application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer

Journal Article · Tue Oct 01 04:00:00 EDT 1985 · Am. J. Surg.; (United States)

DOI:https://doi.org/10.1016/0002-9610(85)90157-6· OSTI ID:6288196

Rosen, I B; Manktelow, R T; Zuker, R M; Boyd, B

Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy protocols. This technique appears to be a dependable, repeatable, and significant advance in management of the patient with head and neck cancer.

• Research Organization: Univ. of Toronto, Ontario, Canada
• OSTI ID: 6288196
• Journal Information: Am. J. Surg.; (United States), Journal Name: Am. J. Surg.; (United States) Vol. 4; ISSN AJSUA
• Country of Publication: United States
• Language: English

Related Subjects

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560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
DIGESTIVE SYSTEM
DISEASES
HEAD
INJURIES
JAW
LOCAL RADIATION EFFECTS
MEDICINE
NECK
NECROSIS
NEOPLASMS
NUCLEAR MEDICINE
ORAL CAVITY
ORGANS
OSTEORADIONECROSIS
PATHOLOGICAL CHANGES
PLASTIC SURGERY
RADIATION EFFECTS
RADIATION INJURIES
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SKELETAL DISEASES
SKELETON
SKULL
SURGERY
THERAPY