Methods of, and apparatus for, proton decoupling in nuclear magnetic resonance spectroscopy

Patent · Tue Jul 21 00:00:00 EDT 1987

OSTI ID:6287119

Vatis, D; Bottomley, P A; Foster, T H

This patent describes an apparatus for providing a radio-frequency signal having at least one selected one of (1) first specie decoupling and (2) nuclear Overhauser enhancement effect, upon a second nuclei specie in a sample in a nuclear magnetic resonance (NMR) experiment, comprising: means for providing a radio-frequency (RF) signal at a center frequency substantially equal to the Larmor frequency of a first specie, different from the second nuclear specie, in the sample; means for modulating the amplitude of the RF signal with a time-dependent sinc (..omega../sub O/t) signal waveform; means for adjusting at least one selected one of (1) the amplitude of the modulated radio-frequency signal and (2) the instantaneous center frequency, across a range of frequencies related to a chemical shift spectrum ..omega../sub O/ of the first specie; and means for applying the adjusted signal to the sample to cause at least one selected one of (1) minimization of the coupling of the first nuclear specie to, and (2) nuclear Overhauser enhancement of, magnetic resonance spectroscopy response signals provided by the second nuclear specie.

• Assignee: General Electric Co., Schenectady, NY
• Patent Number(s): US 4682106
• OSTI ID: 6287119
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
AMPLITUDES
BARYONS
CHEMICAL SHIFT
CONTROL
COUPLING
DECOUPLING
ELEMENTARY PARTICLES
FERMIONS
FREQUENCY CONTROL
FREQUENCY MODULATION
HADRONS
MODULATION
NMR SPECTRA
NUCLEONS
OVERHAUSER EFFECT
PROTONS
RF SYSTEMS
SIGNALS
SPECTRA
TIME DEPENDENCE
WAVE FORMS