Gamma-resonance study of the reaction of iron ions with synthetic L-dopa melanin
The reaction of Fe/sup 3 +/ and Fe/sup 2 +/ ions with synthetic L-dopa melanin, which is a model compound of natural melanin (the melanoprotein granules in the pigment epithelial cells in vertebrate and human eyes), has been studied by gamma-resonance spectroscopy. The investigations showed that L-dopa melanin is capable of effectively binding iron ions and that it displays oxidative or reducing properties with respect to Fe, depending on the composition of the subsystem of the Fe ions and the ambient pH. Trivalent Fe/sup 3 +/ ions form stronger complexes with L-dopa melanin than do Fe/sup 2 +/ ions. The coordination takes place mainly with the carboxyl groups and the amino and imino groups of the polymer. The conformational state of the polymer apparently changes as the pH is varied.
- OSTI ID:
- 6280482
- Journal Information:
- Sov. J. Coordinat. Chem.; (United States), Vol. 11:9; Other Information: Translated from Koordinatsionnaya Khimiya; 11: No.9, 1234-1239(Sep 1985)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
74 ATOMIC AND MOLECULAR PHYSICS
DOPA
GAMMA SPECTRA
HYPERFINE STRUCTURE
REDOX POTENTIAL
IRON COMPLEXES
IRON COMPOUNDS
VALENCE
MELANIN
BINDING ENERGY
COMPLEXOMETRY
ELECTRON SPIN RESONANCE
IRON CHLORIDES
ISOMER SHIFT
J-J COUPLING
L-S COUPLING
LIGANDS
MOESSBAUER EFFECT
PARAMAGNETISM
RELAXATION
RESPONSE MODIFYING FACTORS
SPIN
AMINO ACIDS
ANGULAR MOMENTUM
AUTONOMIC NERVOUS SYSTEM AGENTS
CARBOXYLIC ACIDS
CHLORIDES
CHLORINE COMPOUNDS
COMPLEXES
COUPLING
DRUGS
ENERGY
HALIDES
HALOGEN COMPOUNDS
HYDROXY ACIDS
HYDROXY COMPOUNDS
INTERMEDIATE COUPLING
MAGNETIC RESONANCE
MAGNETISM
NEUROREGULATORS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PARTICLE PROPERTIES
PIGMENTS
RESONANCE
SPECTRA
TRANSITION ELEMENT COMPLEXES
TRANSITION ELEMENT COMPOUNDS
550200* - Biochemistry
640302 - Atomic
Molecular & Chemical Physics- Atomic & Molecular Properties & Theory