Evaluation of the potential carcinogenicity of ethylene oxide (75-21-8). Final report
Technical Report
·
OSTI ID:6277503
Ethylene oxide is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Limited. The potency factor (F) for ethylene oxide is estimated to be 1.34 (mg/kg/day)-1, placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, ethylene oxide is assigned a MEDIUM hazard ranking.
- Research Organization:
- Syracuse Research Corp., NY (United States)
- OSTI ID:
- 6277503
- Report Number(s):
- PB-93-192375/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
29 ENERGY PLANNING, POLICY, AND ECONOMY
290300* -- Energy Planning & Policy-- Environment
Health
& Safety
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKENES
CARCINOGENS
DATA PROCESSING
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
ETHYLENE
HAZARDOUS MATERIALS
HYDROCARBONS
MATERIALS
NATIONAL ORGANIZATIONS
NEOPLASMS
ORGANIC COMPOUNDS
PHYSIOLOGY
PROCESSING
PUBLIC HEALTH
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT
290300* -- Energy Planning & Policy-- Environment
Health
& Safety
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKENES
CARCINOGENS
DATA PROCESSING
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
ETHYLENE
HAZARDOUS MATERIALS
HYDROCARBONS
MATERIALS
NATIONAL ORGANIZATIONS
NEOPLASMS
ORGANIC COMPOUNDS
PHYSIOLOGY
PROCESSING
PUBLIC HEALTH
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT