Evaluation of the potential carcinogenicity of dimethyl sulfate (77-78-1). Final report

Technical Report · Wed Jun 01 00:00:00 EDT 1988

OSTI ID:6277481

Dimethyl sulfate is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Inadequate. Data available are inadequate for calculating a potency factor (F) and no quantitative inferences can be made. Dimethyl sulfate is, therefore, assigned to the median potency factor range and placed in potency group 2 under the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, dimethyl sulfate is assigned a MEDIUM hazard ranking.

• Research Organization: Syracuse Research Corp., NY (United States)
• OSTI ID: 6277481
• Report Number(s): PB-93-194322/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
• Country of Publication: United States
• Language: English

Related Subjects

29 ENERGY PLANNING, POLICY, AND ECONOMY
290300* -- Energy Planning & Policy-- Environment
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& Safety
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOGENS
CHALCOGENIDES
DATA PROCESSING
DIMETHYL SULFIDE
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
MATERIALS
NATIONAL ORGANIZATIONS
NEOPLASMS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
OXYGEN COMPOUNDS
PHYSIOLOGY
PROCESSING
PUBLIC HEALTH
QUANTIZATION
REGULATORY GUIDES
RISK ASSESSMENT
SULFATES
SULFIDES
SULFUR COMPOUNDS
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT