Rapid communication: stochastic model of free-radical yields in oriented DNA exposed to densely ionizing radiation at 77K. Scientific report

Technical Report · Fri Jan 01 00:00:00 EST 1988

OSTI ID:6275486

Miller, J H; Wilson, W E; Swenberg, C E; Myers, L S; Charlton, D E

Monte Carlo simulation techniques were used to calculate the probability that thymine radical anions, formed by the slowing-down of high-energy protons in oriented DNA, will undergo a secondary protonation reaction. By assuming a large asymmetry in the thermal conductivity of oriented DNA fibers, a significant enhancement is predicted of protonation of thymine radical anions when the proton flux is incident on the sample parallel to the orientation of the DNA. These results are in qualitative agreement with experimental data on the production of Thymine radicals when oriented DNA is exposed to fast neutrons.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA)
• OSTI ID: 6275486
• Report Number(s): AD-A-202972/6/XAB
• Resource Relation: Other Information: Pub. in International Jnl. of Radiation Biology, Vol. 53, No. 6, 901-907(1988)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DNA
BIOLOGICAL RADIATION EFFECTS
THYMINE
ANIONS
ASYMMETRY
EXPERIMENTAL DATA
FAST NEUTRONS
FIBERS
MATHEMATICAL MODELS
MONTE CARLO METHOD
NEUTRON FLUX
PRODUCTION
PROGRESS REPORT
PROTONS
RADICALS
SIMULATION
STOCHASTIC PROCESSES
THERMAL CONDUCTIVITY
AZINES
BARYONS
BIOLOGICAL EFFECTS
CHARGED PARTICLES
DATA
DOCUMENT TYPES
ELEMENTARY PARTICLES
FERMIONS
HADRONS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
INFORMATION
IONS
NEUTRONS
NUCLEIC ACIDS
NUCLEONS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHYSICAL PROPERTIES
PYRIMIDINES
RADIATION EFFECTS
RADIATION FLUX
THERMODYNAMIC PROPERTIES
URACILS
560162* - Radionuclide Effects
Kinetics
& Toxicology- Animals
Plants
Microorganisms
& Cells