Dose-response analyses among atomic bomb survivors exposed to low-level radiation

Journal Article · Fri May 01 04:00:00 EDT 1987 · Health Phys.; (United States)

DOI:https://doi.org/10.1097/00004032-198705000-00017· OSTI ID:6273467

Kato, H; Schull, W J; Awa, A; Akiyama, M; Otake, M

An analysis of the dose response within the low-dose range (as here defined, doses of less than 50 cGy (50 rad) was conducted among A-bomb survivors in the ABCC-RERF cohort in an attempt to detect the phenomenon of radiation hormesis, if it is present. These studies include as endpoints cancer mortality, cancer incidence, the frequency of cells with chromosomal aberrations, the phytohemagglutinin response of peripheral lymphocytes and the frequency of mental retardation among survivors exposed in utero. In general, the dose response for these indices of radiation damage varied among comparison groups within the low-dose range, but failed to suggest the existence of radiation hormesis.

• Research Organization: Radiation Effects Research Foundation, Hiroshima, Japan
• OSTI ID: 6273467
• Journal Information: Health Phys.; (United States), Journal Name: Health Phys.; (United States) Vol. 5; ISSN HLTPA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
A-BOMB SURVIVORS
ANIMAL CELLS
ASIA
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHROMOSOMAL ABERRATIONS
CONNECTIVE TISSUE CELLS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ENERGY TRANSFER
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
HEMIC DISEASES
HUMAN POPULATIONS
INJURIES
IRRADIATION
JAPAN
LET
LEUKEMIA
LEUKOCYTES
LOW DOSE IRRADIATION
LYMPHOCYTES
MATERIALS
MENTAL DISORDERS
MUTATIONS
NEOPLASMS
POPULATIONS
RADIATION EFFECTS
RADIATION INJURIES
SOMATIC CELLS