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Reaction of tert-butoxy radicals with phenols. Comparison with the reactions of carbonyl triplets

Journal Article · · J. Am. Chem. Soc.; (United States)
DOI:https://doi.org/10.1021/ja00404a030· OSTI ID:6268195
Tert-butoxy radicals generated in the photodecomposition of di-tert-butyl peroxide react efficiently with phenols to yield the corresponding phenoxy radicals. Typical rate constants in benzene at 22/sup 0/C are 3.3 x 10/sup 8/ and 1.6 x 10/sup 9/ M/sup -1/ s/sup -1/ for phenol and p-methoxyphenol, respectively. The process is considerably slower in polar solvents; e.g., when pyridine is used as cosolvent, the rate constant for phenol drops to 4.1 x 10/sup 6/ M/sup -1/ s/sup -1/ as a result of strong hydrogen bonding which decreases the reactivity of the phenolic O-H group. Isotope effects (H/D) are typically in the 3 to 5 range. 5 figures, 4 tables.
Research Organization:
Univ. of Notre Dame, IN
OSTI ID:
6268195
Journal Information:
J. Am. Chem. Soc.; (United States), Journal Name: J. Am. Chem. Soc.; (United States) Vol. 103:14; ISSN JACSA
Country of Publication:
United States
Language:
English