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Distribution and self-organization of photosynthetic pigments in micelles: Implication for the assembly of light-harvesting complexes and reaction centers in the photosynthetic membrane

Journal Article · · Proceedings of the National Academy of Sciences of the United States of America; (USA)
; ;  [1]
  1. Weizmann Institute of Science, Rehovot (Israel)

The addition of bacteriochlorophylls and bacteriopheophytins to formamide/water, 3:1 (vol/vol), (or water) containing small spherical micelles of Triton X-100 leads to the reorganization of the detergent into micelles that consist of 5,000-40,000 amphiphilic molecules. The pigment distribution within the micelles was determined by modified Poisson statistics taking into consideration the various sizes of micelles. Pigment dimerization occurred in micelles with more than a single occupant and was driven by a free-energy change of {minus}4.5 kcal/mol for bacteriochlorophyll a in formamide/water, {minus}7.6 kcal/mol for bacteriopheophytin a in formamide/water, and {minus}6.6 kcal/mol for bacteriopheophytin a in water. These values correspond to the room temperature equilibrium constants 2.2 {times} 10{sup 3} M{sup {minus}1}, 3.9 {times} 10{sup 5} M{sup {minus}1}, and 7.5 {times} 10{sup 4} M{sup {minus}1}, respectively. The incorporation of bacteriochlorophylls with attached small formamide polymers and the subsequent dimerization of these pigments in the lipid phase provide a model for studying the synergetic organization of polypeptides and bacteriochlorophyll clusters in the photosynthetic membrane.

OSTI ID:
6265749
Journal Information:
Proceedings of the National Academy of Sciences of the United States of America; (USA), Journal Name: Proceedings of the National Academy of Sciences of the United States of America; (USA) Vol. 87:14; ISSN 0027-8424; ISSN PNASA
Country of Publication:
United States
Language:
English