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Adverse pregnancy outcome: sensitive periods, types of adverse outcomes, and relationships with critical exposure periods

Journal Article · · Prog. Clin. Biol. Res.; (United States)
OSTI ID:6265374
A wide variety of agents has been demonstrated to be capable of affecting the fetus in utero. Certain generalizations can be made concerning these teratogens. Two of the most important of these principles are the specificity of the agent and the time during gestation of the exposure. Although noticeable adverse effects are structural malformations, there are numerous functional malformations, such as lower intelligence and poor reproductive outcome, that may follow exposure to these agents. There is some evidence that future behavior may be affected by in utero teratogen exposure; however, this field has been infrequently investigated and no firm conclusions can be drawn.
Research Organization:
Univ. of Utah Medical Center, Salt Lake City
OSTI ID:
6265374
Journal Information:
Prog. Clin. Biol. Res.; (United States), Journal Name: Prog. Clin. Biol. Res.; (United States) Vol. 160; ISSN PCBRD
Country of Publication:
United States
Language:
English

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