Lack of photoprotection against UVB-induced erythema by immediate pigmentation induced by 382 nm radiation

Journal Article · Thu Oct 31 23:00:00 EST 1985 · J. Invest. Dermatol.; (United States)

DOI:https://doi.org/10.1111/1523-1747.ep12277170· OSTI ID:6255243

Black, G; Matzinger, E; Gange, R W

Immediate pigment darkening (IPD) was induced on the backs of 11 human volunteers of skin types III and IV by exposing the skin to UVA radiation (382 nm). The minimum erythema dose (MED) of UVB radiation was also determined by exposing sites to graduated doses of 304 nm radiation. The order of exposure of distinct anatomic areas was as follow: UVB followed by IPD induction; IPD induction followed by UVB; IPD induction followed 3 h later by UVB; and UVB only. Erythema responses induced by UVB were graded by inspection 24 h later and the MEDs in the 4 areas were compared. The induction of IPD before UVB exposure caused no significant change in the MED compared to sites receiving UVB only, or receiving UVA radiation after UVB, confirming that the IPD reaction does not protect against UVB-induced erythema. There was also no evidence of photorecovery, i.e., an increase in the MED of UVB resulting from exposure to longer wavelength, UV or visible radiation following UVB exposure.

• Research Organization: Massachusetts General Hospital, Boston
• OSTI ID: 6255243
• Journal Information: J. Invest. Dermatol.; (United States), Journal Name: J. Invest. Dermatol.; (United States) Vol. 5; ISSN JIDEA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
ELECTROMAGNETIC RADIATION
ERYTHEMA
FAR ULTRAVIOLET RADIATION
MAMMALS
MAN
NEAR ULTRAVIOLET RADIATION
ORGANS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
SKIN
SYMPTOMS
ULTRAVIOLET RADIATION
VERTEBRATES