Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Cytocidal effect of hyperthermia on tumor cells in vivo

Journal Article · · NIDA Res. Monogr.; (United States)
OSTI ID:6254664
The cytocidal effect of hyperthermia on subcutaneous SCK tumor cells growing in vivo was significantly greater than that on the SCK tumor cells cultured in vitro. When the tumors were left in situ after heating, the cell survival progressively decreased, and the functional intratumor vascular volume also decreased. The radiation survival curves of tumor cells heated either 30 minutes before or after X-irradiation in vivo were steeper than the radiation survival curve of unheated control tumors. Therefore, the cytocidal effect of hyperthermia on tumor cells in vivo is greater than that in vitro.
Research Organization:
Department of Therapeutic Radiology, University of Minnesota Medical School, Minneapolis
OSTI ID:
6254664
Journal Information:
NIDA Res. Monogr.; (United States), Journal Name: NIDA Res. Monogr.; (United States) Vol. 61; ISSN MIDAD
Country of Publication:
United States
Language:
English