Ionizing radiation and its risks

Journal Article · Wed Dec 01 04:00:00 EST 1982 · West. J. Med.; (United States)

OSTI ID:6253786

Goldman, M

Penetrating ionizing radiation fairly uniformly puts all exposed molecules and cells at approximately equal risk for deleterious consequences. Thus, the original deposition of radiation energy (that is, the dose) is unaltered by metabolic characteristics of cells and tissue, unlike the situation for chemical agents. Intensely ionizing radiations, such as neutrons and alpha particles, are up to ten times more damaging than sparsely ionizing sources such as x-rays or gamma rays for equivalent doses. Furthermore, repair in cells and tissues can ameliorate the consequences of radiation doses delivered at lower rates by up to a factor of ten compared with comparable doses acutely delivered, especially for somatic (carcinogenic) and genetic effects from x- and gamma-irradiation exposure. Studies on irradiated laboratory animals or on people following occupational, medical or accidental exposures point to an average lifetime fatal cancer risk of about 1 x 10/sup -4/ per rem of dose (100 per 10/sup 6/ person-rem). Leukemia and lung, breast and thyroid cancer exposures from natural sources (cosmic rays and terrestrial radioactivity) of about 0.1 rem per year yield a lifetime cancer risk about 0.1 percent of the normally occurring 20 percent risk of cancer death. An increase of about 1 percent per rem in fatal cancer risk, or 200 rem to double the ''background'' risk rate, is compared with an estimate of about 200 rem to double the genetic risk. Newer data suggest that the risks for low-level radiation are lower than risks estimated from data from high exposures and that the present 5 rem per year limit for workers is adequate.

• Research Organization: Univ. of California, Davis
• OSTI ID: 6253786
• Journal Information: West. J. Med.; (United States), Journal Name: West. J. Med.; (United States) Vol. 137:6; ISSN WJMDA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
560152 -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
CARCINOGENESIS
DISEASES
DOSES
EPIDEMIOLOGY
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
HAZARDS
HEALTH HAZARDS
HEMIC DISEASES
IONIZING RADIATIONS
LABORATORY ANIMALS
LEUKEMIA
NEOPLASMS
PATHOGENESIS
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION HAZARDS
RADIATIONS
RECOVERY
REPAIR
RISK ASSESSMENT