Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Iron metabolism study in humans by means of stable tracers

Journal Article · · Med. Phys.; (United States)
DOI:https://doi.org/10.1118/1.596168· OSTI ID:6251869
An investigation of iron metabolism in a female patient volunteer by administration of stable iron isotopes as tracers was performed. The applied methodology had already been tested in rabbits in comparison with radioactive tracer technique. The subject under study was given /sup 58/Fe solution intravenously and about 45 min later /sup 57/Fe solution orally. Ten blood samples were drawn at different times within 522 min from injection. Single iron isotopes content in plasma samples was determined by proton nuclear activation. A Compton suppressor system was utilized to improve the detector limits. The characteristic parameters of iron plasma clearance and of iron intestinal absorption were determined.
Research Organization:
Universita di Milano (Italy)
OSTI ID:
6251869
Journal Information:
Med. Phys.; (United States), Journal Name: Med. Phys.; (United States) Vol. 15:6; ISSN MPHYA
Country of Publication:
United States
Language:
English