Methodology for the measurement and analysis of relaxation times in proton imaging

Journal Article · Thu Jan 01 04:00:00 EST 1987 · Magn. Reson. Imag.; (United States)

DOI:https://doi.org/10.1016/0730-725X(87)90022-1· OSTI ID:6245561

MacFall, J R; Wehrli, F W; Breger, R K; Johnson, G A

Measurements of proton T1 and T2 were performed on GdCl/sub 3/ solutions (20 less than T2 less than 500 msec, 90 less than T1 less than 1000 msec) on large-bore NMR imaging systems operating at 1.0T and 1.5T. CPMG multi-echo (ME), multiple saturation recovery (MSR) and modified fast inversion recovery (MFIR) pulse sequences as well as a sequence that combines and interleaves T1 and T2 weighted data acquisition (which we call multiple saturation-recovery multiple-echo (MSRME) were used. The relaxation data are compared to those obtained on a small bore NMR spectrometer operated at 1.5T. T1 and T2 values for the solutions were found to be the same within 10% for the two fields. Reproducibility of measurements of T1, T2 and the unnormalized spin density of the solutions was better than 5%. Systematic errors, amenable to correction through calibration, are noted in the imager T1 and T2 values. T1 and T2 values for some typical neural tissues at 1.5T and body tissue at 1.0T for human volunteers were obtained and are tabulated.

• Research Organization: General Electric Medical Systems Group, Milwaukee, WI
• OSTI ID: 6245561
• Journal Information: Magn. Reson. Imag.; (United States), Journal Name: Magn. Reson. Imag.; (United States) Vol. 5:3; ISSN MRIMD
• Country of Publication: United States
• Language: English

Related Subjects

550600* -- Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
BARYONS
DIAGNOSTIC TECHNIQUES
DISPERSIONS
ELEMENTARY PARTICLES
ELEMENTS
ERRORS
EVALUATION
FERMIONS
GADOLINIUM
HADRONS
IMAGES
MAGNETIC RESONANCE
MEASURING METHODS
METALS
MIXTURES
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
NUCLEONS
PROTONS
RARE EARTHS
RESONANCE
SOLUTIONS