Toxicological study of ''Aralhex Brush'' and its two components

Technical Report · Sun Sep 01 04:00:00 EDT 1985

OSTI ID:6240087

London, J E; Smith, D M

The acute oral LD/sub 50/ values for the adhesive ''Aralhex Brush'' for mice and rats are greater than 5g/kg. According to classified guidelines, the mixture would be considered only slightly toxic or practically nontoxic in both species. Skin application studies in the rabbit with the adhesive demonstrated that it was cutaneously mildly irritating; however, based on the primary irritation index, the adhesive's two precursor components were nonirritating. The adhesive and components I were mildly irritating in the rabbit eye application studies and component II was non-irritating. The sensitization study in the guinea pig did not show ''Aralhex Brush'' or its two components to be sensitizers. 5 refs., 3 tabs.

• Research Organization: Los Alamos National Lab., NM (USA)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 6240087
• Report Number(s): LA-10531-MS; ON: DE86003299
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ADHESIVES
ANIMALS
BODY
BODY AREAS
DATA
EDEMA
ERYTHEMA
EXPERIMENTAL DATA
EYES
FACE
HEAD
INFLAMMATION
INFORMATION
MAMMALS
MICE
NUMERICAL DATA
ORAL ADMINISTRATION
ORGANS
PATHOLOGICAL CHANGES
RABBITS
RATS
RODENTS
SENSE ORGANS
SKIN ABSORPTION
SYMPTOMS
TOXICITY
UPTAKE
VERTEBRATES