Evaluation of the potential carcinogenicity of bis(chloromethyl)ether. Final report

Technical Report · Wed Jun 01 04:00:00 EDT 1988

OSTI ID:6238066

Bis(chloromethyl)ether is a human carcinogen, classified as weight-of-evidence Group A under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Sufficient. The potency factor (F) for bis(chloromethyl)ether is estimated to be 10,377/(mg/kg/day), placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, bis(chloromethyl)ether is assigned a HIGH hazard ranking for the purposes of RQ adjustment.

• Research Organization: Syracuse Research Corp., NY (United States)
• OSTI ID: 6238066
• Report Number(s): PB-93-185080/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
• Country of Publication: United States
• Language: English

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