Pineal and ectopic pineal tumors: the role of radiation therapy. [X ray; /sup 60/Co]

Conference · Sat Aug 01 00:00:00 EDT 1981 · Cancer; (United States)

OSTI ID:6229359

Rao, Y T.R.; Medini, E; Haselow, R E; Jones, Jr, T K; Levitt, S H

Seventeen patients with pineal tumors and one ectopic (suprasellar) germinoma were treated with radiation therapy. Surgery was restricted to decompression in 16 patients, and only two patients had resection of the tumor. Thirteen of 18 patients are alive without evidence for disease with a ten-year surrvival rate of 88%. The tumor dose ranged from 4000 rads to 6000 rads. No age or dose dependence in survival was noted, but patients with whole brain irradiation or generous volume to include ventricular system had better survival. No case of spinal metastasis was noted. The possibility of increased incidence of meningeal seeding following surgical intervention is considered. From their data, the authors feel that radiation therapy with or without surgical decompression should be the primary treatment for pinealoma. Surgery can be used for diagnosis and/or treatment of patients who show delayed response to radiation. Recommendation is made for the use of whole brain irradiation to 4000 rads followed by a boost to the tumor area to 5000 rads.

• Research Organization: Univ. of Minnesota, Minneapolis
• OSTI ID: 6229359
• Journal Information: Cancer; (United States), Vol. 48:3; Conference: 66. scientific assembly and annual meeting of the Radiological Society of North America, Dallas, Texas, USA, 16 Nov 1980
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
ATROPHY
RADIOINDUCTION
EYES
BIOLOGICAL RADIATION EFFECTS
NERVOUS SYSTEM DISEASES
RADIOTHERAPY
SIDE EFFECTS
COBALT 60
GAMMA RADIATION
LINEAR ACCELERATORS
LOCAL IRRADIATION
METASTASES
PATIENTS
PINEAL GLAND
SURGERY
X RADIATION
ACCELERATORS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
BODY AREAS
COBALT ISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
FACE
GLANDS
HEAD
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
SENSE ORGANS
THERAPY
YEARS LIVING RADIOISOTOPES
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)