Equilibrium radionuclide gated angiography in patients with tricuspid regurgitation

Journal Article · Sat Jan 15 00:00:00 EST 1983 · Am. J. Cardiol.; (United States)

DOI:https://doi.org/10.1016/S0002-9149(83)80055-1· OSTI ID:6224319

Handler, B; Pavel, D G; Pietras, R; Swiryn, S; Byrom, E; Lam, W; Rosen, K M

Equilibrium gated radionuclide angiography was performed in 2 control groups (15 patients with no organic heart disease and 24 patients with organic heart disease but without right- or left-sided valvular regurgitation) and in 9 patients with clinical tricuspid regurgitation. The regurgitant index, or ratio of left to right ventricular stroke counts, was significantly lower in patients with tricuspid regurgitation than in either control group. Time-activity variation over the liver was used to compute a hepatic expansion fraction which was significantly higher in patients with tricuspid regurgitation than in either control group. Fourier analysis of time-activity variation in each pixel was used to generate amplitude and phase images. Only pixels with values for amplitude at least 7% of the maximum in the image were retained in the final display. All patients with tricuspid regurgitation had greater than 100 pixels over the liver automatically retained by the computer. These pixels were of phase comparable to that of the right atrium and approximately 180 degrees out of phase with the right ventricle. In contrast, no patient with no organic heart disease and only 1 of 24 patients with organic heart disease had any pixels retained by the computer. In conclusion, patients with tricuspid regurgitation were characterized on equilibrium gated angiography by an abnormally low regurgitant index (7 of 9 patients) reflecting increased right ventricular stroke volume, increased hepatic expansion fraction (7 of 9 patients), and increased amplitude of count variation over the liver in phase with the right atrium (9 of 9 patients).

• Research Organization: Department of Medicine, Abraham Lincoln School of Medicine, University of Illinois, Chicago
• OSTI ID: 6224319
• Journal Information: Am. J. Cardiol.; (United States), Vol. 51:2
• Country of Publication: United States
• Language: English

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