Imaging of a parapharyngeal hemangiopericytoma. Radioimmunoscintigraphy (SPECT) with indium-111-labeled anti-CEA antibody, and comparison to digital subtraction angiography, computed tomography, and immunohistochemistry

Journal Article · Tue Jan 01 00:00:00 EST 1991 · Cancer (Philadelphia); (USA)

DOI:https://doi.org/10.1002/1097-0142(19910101)67:1<61::AID-CNCR2820670112>3.0.CO;2-V· OSTI ID:6213242

Kairemo, K J; Hopsu, E V; Melartin, E J; Heikkilae, P S ^[1]

---

1. Helsinki Univ. Central Hospital (Finland)

A 27-year-old male patient with a parapharyngeal hemangiopericytoma was investigated radiologically with orthopantomography, computed tomography, and digital subtraction angiography before the operation. Because a malignancy was suspected, the patient was imaged with gamma camera using radiolabeled monoclonal anticarcinoembryonal antigen antibody including single photon emission computed tomography. The radioantibody accumulated strongly into the neoplasm. Tumor to background ratio was 2.2. Samples of the excised tumor were stained immunohistochemically for desmin, vimentin, muscle actin, cytokeratin, CEA (carcinoembryonic antigen), and factor VIII. They showed that the antibody uptake was of unspecific nature and not due to CEA expression in the tumor.

• OSTI ID: 6213242
• Journal Information: Cancer (Philadelphia); (USA), Vol. 67:1; ISSN 0008-543X
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
DIAGNOSTIC TECHNIQUES
COMPARATIVE EVALUATIONS
NEOPLASMS
DIAGNOSIS
PHARYNX
CEA
GAMMA CAMERAS
IMMUNOASSAY
INDIUM 111
MONOCLONAL ANTIBODIES
PATIENTS
RADIOIMMUNOSCINTIGRAPHY
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
ANTIBODIES
BETA DECAY RADIOISOTOPES
BIOASSAY
BODY
CAMERAS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
FRENCH ORGANIZATIONS
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MINUTES LIVING RADIOISOTOPES
NATIONAL ORGANIZATIONS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOIMMUNODETECTION
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
SCINTISCANNING
TOMOGRAPHY
TRACER TECHNIQUES
550601* - Medicine- Unsealed Radionuclides in Diagnostics