Recognition of distinctive patterns of gallium-67 distribution in sarcoidosis

Journal Article · Sat Dec 01 00:00:00 EST 1990 · Journal of Nuclear Medicine; (USA)

OSTI ID:6208684

Sulavik, S B; Spencer, R P; Weed, D A; Shapiro, H R; Shiue, S T; Castriotta, R J ^[1]

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1. Univ. of Connecticut School of Medicine, Farmington (USA)

Assessment of gallium-67 ({sup 67}Ga) uptake in the salivary and lacrimal glands and intrathoracic lymph nodes was made in 605 consecutive patients including 65 with sarcoidosis. A distinctive intrathoracic lymph node {sup 67}Ga uptake pattern, resembling the Greek letter lambda, was observed only in sarcoidosis (72%). Symmetrical lacrimal gland and parotid gland {sup 67}Ga uptake (panda appearance) was noted in 79% of sarcoidosis patients. A simultaneous lambda and panda pattern (62%) or a panda appearance with radiographic bilateral, symmetrical, hilar lymphadenopathy (6%) was present only in sarcoidosis patients. The presence of either of these patterns was particularly prevalent in roentgen Stages I (80%) or II (74%). We conclude that simultaneous (a) lambda and panda images, or (b) a panda image with bilateral symmetrical hilar lymphadenopathy on chest X-ray represent distinctive patterns which are highly specific for sarcoidosis, and may obviate the need for invasive diagnostic procedures.

• OSTI ID: 6208684
• Journal Information: Journal of Nuclear Medicine; (USA), Vol. 31:12; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GALLIUM 67
UPTAKE
LYMPH NODES
RADIONUCLIDE KINETICS
SALIVARY GLANDS
NERVOUS SYSTEM DISEASES
PATIENTS
BETA DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM ISOTOPES
GLANDS
INTERMEDIATE MASS NUCLEI
ISOTOPES
LYMPHATIC SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man