Omaha childhood blood lead and environmental lead: a linear total exposure model

Journal Article · Mon Oct 01 04:00:00 EDT 1984 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(84)90123-3· OSTI ID:6208150

Angle, C R; Marcus, A; Cheng, I H; McIntire, M S

The majority of experimental and population studies of blood lead (PbB) and environmental lead, including the Omaha study, have utilized the Goldsmith-Hexter log-log or power function model. Comparison was made of the log-log model and a linear model of total exposure as they described the Omaha Study of 1074 PbBs from children ages 1-18 years as related to air (PbA), soil (PbS), and housedust (PbHD) lead. The data fit of the linear model was statistically equivalent to the power model and the predicted curves were biologically more plausible. The linear model avoids the mathematical limitations of the power model which predicts PbB zero at PbA zero. From the Omaha data, this model, ln PbB = ln (..beta../sub 0/ + B/sub 1/ PbA + B/sub 2/ PbS + ..beta../sub 3/ PbHD) predicts that PbB increases 1.92 ..mu..g/dl as PbA increases 1.0 ..mu..g/m/sup 3/. Since PbS and PbHD increase with PbA, however, the increases in total exposure predict a PbB increase of 4-5 ..mu..g/dl as PbA increases 1.0 ..mu..g/m/sup 3/.

• Research Organization: Univ. of Nebraska Medical Center, Omaha
• OSTI ID: 6208150
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 35:1; ISSN ENVRA
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
AIR POLLUTION
BIOLOGICAL ACCUMULATION
BIOLOGICAL MATERIALS
BLOOD
BODY FLUIDS
CHEMICAL ANALYSIS
CHILDREN
DATA
DUSTS
ELEMENTS
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FEDERAL REGION VII
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MATHEMATICAL MODELS
METALS
MONITORING
NEBRASKA
NORTH AMERICA
NUMERICAL DATA
POLLUTION
SOILS
STATISTICAL DATA
USA