Defective bursa regeneration after irradiation of young thymectomized chickens
Journal Article
·
· Cell. Immunol.; (United States)
The ability of the bursa of Fabricius to regenerate after gamma-irradiation and bone marrow reconstitution was examined in chickens thymectomized (TX) immediately after hatching. Irradiation (2 X 500 R) 3 weeks after hatching was followed by impaired bursa regeneration, as judged both by bursa/body weight ratios and by bursa follicle development 3-6 weeks later in TX as compared to control birds. Germinal center formation in the spleen was deficient, and immune responses to sheep erythrocytes (SRBC) and B. abortus (BA) were moderately reduced in the TX as compared to control birds irradiated at 3 weeks but not in TX birds irradiated at 5 weeks of age.
- Research Organization:
- New York Univ. Medical Center, NY
- OSTI ID:
- 6201281
- Journal Information:
- Cell. Immunol.; (United States), Journal Name: Cell. Immunol.; (United States) Vol. 87:1; ISSN CLIMB
- Country of Publication:
- United States
- Language:
- English
Similar Records
Cellular composition of the bone marrow in the chicken. II. Effect of age and the influence of the bursa of Fabricius on the size of cellular compartments
Protection against apoptosis in chicken bursa and thymus cells by phorbol ester in vitro
Physiological effects of mercury in the domestic chicken
Journal Article
·
Wed Dec 31 23:00:00 EST 1980
· Anat. Rec.; (United States)
·
OSTI ID:5995758
Protection against apoptosis in chicken bursa and thymus cells by phorbol ester in vitro
Conference
·
Thu Mar 14 23:00:00 EST 1991
· FASEB Journal (Federation of American Societies for Experimental Biology); (United States)
·
OSTI ID:5214334
Physiological effects of mercury in the domestic chicken
Journal Article
·
Sun Dec 31 23:00:00 EST 1972
· Environ. Health Perspect.; (United States)
·
OSTI ID:5119458
Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REGENERATION
BIRDS
BODY
BONE MARROW
CHICKENS
CHIMERAS
ELECTROMAGNETIC RADIATION
FOWL
GAMMA RADIATION
HEMATOPOIETIC SYSTEM
IMMUNE REACTIONS
INHIBITION
IONIZING RADIATIONS
MEDICINE
MOSAICISM
ORGANS
RADIATION CHIMERAS
RADIATION EFFECTS
RADIATIONS
RECOVERY
SURGERY
THYMECTOMY
TISSUES
VERTEBRATES
WEIGHT
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REGENERATION
BIRDS
BODY
BONE MARROW
CHICKENS
CHIMERAS
ELECTROMAGNETIC RADIATION
FOWL
GAMMA RADIATION
HEMATOPOIETIC SYSTEM
IMMUNE REACTIONS
INHIBITION
IONIZING RADIATIONS
MEDICINE
MOSAICISM
ORGANS
RADIATION CHIMERAS
RADIATION EFFECTS
RADIATIONS
RECOVERY
SURGERY
THYMECTOMY
TISSUES
VERTEBRATES
WEIGHT