In vitro prostaglandin E2 stimulation of /sup 45/Ca mobilization from chick bone
Journal Article
·
· Poult. Sci.; (United States)
The ability of prostaglandin E2 (PGE2) to mobilize /sup 45/Ca from chick embryo long bones was assayed in an in vitro bone culture system. Concentrations of PGE2 tested ranged from 10(-9) to 10(-5) M. The PGE2 was effective in stimulating release of /sup 45/Ca from prelabelled bones at all concentrations tested except at 10(-9) M. In addition, stimulation of /sup 45/Ca release could be produced daily for 4 consecutive days of PGE2 culture-pulsing at what appeared to be the optimal PGE2 concentration, 10(-7) M. The authors conclude, as in mammals, PGE2 is a potent stimulator of calcium mobilization from avian bone. The potential involvement of prostaglandins in eggshell formation is discussed.
- Research Organization:
- Louisiana State Univ., Baton Rouge
- OSTI ID:
- 6200896
- Journal Information:
- Poult. Sci.; (United States), Journal Name: Poult. Sci.; (United States) Vol. 63:4; ISSN POSCA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ANIMAL TISSUES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOCHEMISTRY
BIRDS
BODY
BONE TISSUES
CALCIUM 45
CALCIUM ISOTOPES
CHEMISTRY
CHICKENS
CONNECTIVE TISSUE
DAYS LIVING RADIOISOTOPES
DIFFUSION
EMBRYOS
EVEN-ODD NUCLEI
FOWL
IN VITRO
INTERMEDIATE MASS NUCLEI
ISOTOPES
NUCLEI
ORGANS
PROSTAGLANDINS
RADIOISOTOPES
RADIONUCLIDE KINETICS
SKELETON
TISSUES
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ANIMAL TISSUES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOCHEMISTRY
BIRDS
BODY
BONE TISSUES
CALCIUM 45
CALCIUM ISOTOPES
CHEMISTRY
CHICKENS
CONNECTIVE TISSUE
DAYS LIVING RADIOISOTOPES
DIFFUSION
EMBRYOS
EVEN-ODD NUCLEI
FOWL
IN VITRO
INTERMEDIATE MASS NUCLEI
ISOTOPES
NUCLEI
ORGANS
PROSTAGLANDINS
RADIOISOTOPES
RADIONUCLIDE KINETICS
SKELETON
TISSUES
VERTEBRATES