Relationship of blood cadmium level to hypertension and plasma norepinephrine level: a Romanian study (41159)

Journal Article · Mon Jun 01 04:00:00 EDT 1981 · Proc. Soc. Exp. Biol. Med.; (United States)

DOI:https://doi.org/10.3181/00379727-167-41159· OSTI ID:6187335

Revis, N W; Zinsmeister, A R

The associations of blood cadmium levels with hypertension and plasma norepinephrine concentrations were determined in normotensive and hypertensive nonsmokers and smokers. Statistical analysis showed that after adjustment for age alone, the estimated mean values of blood cadmium and plasma norepinephrine in nonsmokers were significantly lower than in smokers. However, after adjustment for age and blood cadmium, the estimated mean values for plasma norepinephrine were not significantly different between nonsmokers and smokers or normotensives and hypertensives. In contrast the estimated mean value for blood cadmium as a function of blood pressure and smoking habit was still significant after adjustment for age and plasma norepinephrine. We suggest that smoking and blood pressure affect the level of blood cadmium, and through this change in blood cadmium the level of plasma norepinephrine is affected.

• Research Organization: Oak Ridge National Lab., TN
• DOE Contract Number: W-7405-ENG-26
• OSTI ID: 6187335
• Journal Information: Proc. Soc. Exp. Biol. Med.; (United States), Journal Name: Proc. Soc. Exp. Biol. Med.; (United States) Vol. 167:2; ISSN PSEBA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL HORMONES
AEROSOLS
AGE GROUPS
AUTONOMIC NERVOUS SYSTEM AGENTS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CHEMISTRY
BLOOD PLASMA
BLOOD PRESSURE
BODY FLUIDS
CADMIUM COMPOUNDS
CARDIOTONICS
CARDIOVASCULAR AGENTS
CARDIOVASCULAR DISEASES
CATIONS
CHARGED PARTICLES
COLLOIDS
CORRELATIONS
DISEASES
DISPERSIONS
DRUGS
HORMONES
HUMAN POPULATIONS
HYPERTENSION
IONS
MATERIALS
NEUROREGULATORS
NORADRENALINE
PATHOLOGICAL CHANGES
POPULATIONS
RESIDUES
SMOKES
SOLS
STEROID HORMONES
SYMPATHOMIMETICS
SYMPTOMS
TOBACCO SMOKES
VASCULAR DISEASES