Teratologic studies of prenatal exposure of rats to 915-MHz microwave radiation

Journal Article · Fri Oct 01 04:00:00 EDT 1982 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575851· OSTI ID:6159994

Jensh, R P; Weinberg, I; Brent, R L

Thirty-nine pregnant Wistar strain albino rats were used to determine possible teratogenic activity due to chronic exposure with microwave radiation at a field intensity of a 10 mW/cm/sup 2/ at a frequency of 915-MHz microwave radiation. Ten rats were irradiated in a fully characterized anechoic chamber from Days 1 to 21 of gestation. The results of preliminary studies using 20 pregnant rats indicated that this power density was the maximal level which did not cause increased rectal temperature. Twenty-nine pregnant females were used as control animals. On the 22nd day of gestation animals were killed and maternal brain, liver, kidneys, and ovaries were removed, examined, weighed, and fixed in buffered formalin. Fetuses and placentae were removed, examined, weighed, and fixed in Bouin's fixative. All fetuses were examined for malformations using a cross-section dissection methodology.No significant alterations were observed for the following parameters; maternal body weight and weight gain, term maternal organ weight and organ/body weight ratios, resorption rate, abnormality rate, mean term litter size, or mean term fetal weight. No significant teratogenic activity was observed, using these criteria, due to chronic exposure of pregnant rats to 915-MHz continuous wave microwave radiation at a 10 mW/cm/sup 2/ power density.

• Research Organization: Thomas Jefferson Univ., Philadelphia, PA
• OSTI ID: 6159994
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 92:1; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CHRONIC EXPOSURE
CHRONIC IRRADIATION
CONGENITAL MALFORMATIONS
DIGESTIVE SYSTEM
ELECTROMAGNETIC RADIATION
FEMALE GENITALS
FETUSES
FREQUENCY RANGE
GLANDS
GONADS
IRRADIATION
KIDNEYS
LIVER
MALFORMATIONS
MAMMALS
MHZ RANGE
MHZ RANGE 100-1000
MICROWAVE RADIATION
NERVOUS SYSTEM
ORGANS
OVARIES
PATHOLOGICAL CHANGES
PREGNANCY
PRENATAL EXPOSURE
PRENATAL IRRADIATION
RADIATIONS
RATS
RODENTS
TERATOGENESIS
VERTEBRATES