Molybdenum catalysts for allylic alkylation

Journal Article · Wed Oct 06 00:00:00 EDT 1982 · J. Am. Chem. Soc.; (United States)

DOI:https://doi.org/10.1021/ja00384a071· OSTI ID:6158908

Trost, B M; Lautens, M

This paper reports on the stoichiometric and catalytic allylic substituion reactions involving molybdenum complexes and the sensitivity of regioselectivity toward the nature of the ligands on molybdenum. Results indicated that the allylic alkylation catalyzed by molybdenum forms a useful and frequently complementary alternative to the palladium-catalyzed reaction. For example, regioselectivity appears more sensitive to ligand variation in the case of Mo. Higher selectivity for attach at a primary vs. secondary carbon of a ..pi..-allyl fragment occurs with Mo. It also appears that more flexibility in stereocontrol may exist. On the other hand, these reactions require higher temperatures and longer times. More thorough evaluation of this Mo chemistry will be required to delineate its full potential.

• Research Organization: Univ. of Wisconsin, Madison
• OSTI ID: 6158908
• Journal Information: J. Am. Chem. Soc.; (United States), Journal Name: J. Am. Chem. Soc.; (United States) Vol. 104:20; ISSN JACSA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201 -- Chemical & Physicochemical Properties
400301* -- Organic Chemistry-- Chemical & Physicochemical Properties-- (-1987)
ACETATES
ALKENES
ALKYLATION
CARBOXYLIC ACID SALTS
CATALYSTS
CATALYTIC EFFECTS
CHEMICAL REACTIONS
COMPLEXES
ELEMENTS
HYDROCARBONS
METALS
MOLYBDENUM
MOLYBDENUM COMPLEXES
NITROGEN
NONMETALS
ORGANIC COMPOUNDS
TRANSITION ELEMENT COMPLEXES
TRANSITION ELEMENTS