Tissue interaction with nonionizing electromagnetic fields. Final report
Studies of the effects of environmental low frequency electromagnetic fields on isolated cellular systems and tissue preparations derived from brain, bone, blood, and pancreas are reported. Behavioral effects of 60 Hz fields were examined in monkeys. Bioeffects of low level microwave fields modulated at 60 Hz and other ELF frequencies were also examined. Findings in the present studies emphasize a key role for cell membrane surfaces in detecting ELF environmental fields. Two broad groups of exposure techniques have been utilized. In the ELF spectrum, 60 Hz environmental fields were imposed on monkeys during behavioral task performance. Field intensities from 50 to 1000 V/m were tested in different experiments. The monkeys were exposed to a horizontal electric field. In tissue and cell culture preparations, ELF electric fields were generated by passing current between electrodes in the solutions bathing the tissue. Tissue and cell preparations were also tested with low frequency, pulsed magnetic fields by placing the biological preparation inside Helmholtz coils. For ELF dosimetry measurements in tissue preparations, electric gradients were measured directly in relation to specific axes of tissue and cell preparations. Exposures to ELF modulated 450 MHz microwave fields were conducted in two different systems, one uses a large anechoic horn chamber, the other utilizes a Crawford cell, a double-tapered coaxial system.Environmental field levels and tissue components of these fields were studied collaboratively using implantable tissue probes developed by BRH. Concurrent environmental field levels were based on measurements with other BRH probes and a NARDA microwave probe system. (ERB)
- Research Organization:
- Veterans Administration Hospital, Loma Linda, CA (USA); California Univ., Riverside (USA)
- DOE Contract Number:
- AT01-79ET29078
- OSTI ID:
- 6149860
- Report Number(s):
- DOE/ET/29078-T1; ON: DE81027654
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
BRAIN
BIOLOGICAL FUNCTIONS
ELECTROMAGNETIC FIELDS
BIOLOGICAL EFFECTS
LYMPHOCYTES
MONKEYS
BEHAVIOR
NERVE CELLS
CELL CULTURES
COMPARATIVE EVALUATIONS
HZ RANGE
MHZ RANGE
TISSUE CULTURES
ANIMAL CELLS
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CENTRAL NERVOUS SYSTEM
CONNECTIVE TISSUE CELLS
FREQUENCY RANGE
FUNCTIONS
LEUKOCYTES
MAMMALS
MATERIALS
NERVOUS SYSTEM
ORGANS
PRIMATES
SOMATIC CELLS
VERTEBRATES
560400* - Other Environmental Pollutant Effects
550100 - Behavioral Biology
550300 - Cytology
551000 - Physiological Systems