Radiation in multidisciplinary treatment of children with malignant ovarian tumors
Thirteen girls with malignant ovarian tumors treated at Memorial Hospital fromm August 1971 through October 1975 with extensive surgery, multi-drug chemotherapy (T-2 protocol) and postoperative radiation were reviewed. The plan of radiation was to deliver 3,000 rads to the whole abdomen and boost the para-aortic and pelvic area with 1,500 rads in five to six weeks. In only two patients was the radiation conducted as planned. In others the treatment was either interrupted or discontinued due to complications. Four of the thirteen patients are dead. The cause of death in two of these patients was distant metastases; the two other patients died without evidence of tumor due to treatment complications. Three of the nine patients who are alive without evidence of disease have late complications. Following radical surgery, lower doses of radiation given concomitantly with T-2 protocol chemotherapy seem to be sufficient for controlling the disease.
- Research Organization:
- Memorial Sloan-Kettering Cancer Center, New York
- OSTI ID:
- 6137950
- Journal Information:
- Cancer; (United States), Vol. 43:3; Conference: New Orleans, LA, USA, April 26--30, 1978; Other Information: 60. annual meeting of the American Radium society
- Country of Publication:
- United States
- Language:
- English
Similar Records
Whole Abdominopelvic Intensity-Modulated Radiation Therapy for Desmoplastic Small Round Cell Tumor After Surgery
Whole-abdomen radiation therapy in ovarian carcinoma: Its role as a salvage therapeutic modality
Related Subjects
OVARIES
NEOPLASMS
RADIOTHERAPY
SIDE EFFECTS
CHEMOTHERAPY
CHILDREN
EXPERIMENTAL DATA
GRAPHS
ISOLATED VALUES
RADIATION DOSES
SURGERY
SURVIVAL TIME
ANIMALS
BODY
DATA
DATA FORMS
DISEASES
DOSES
FEMALE GENITALS
GONADS
INFORMATION
MAMMALS
MAN
MEDICINE
NUCLEAR MEDICINE
NUMERICAL DATA
ORGANS
PRIMATES
RADIOLOGY
THERAPY
VERTEBRATES
560151* - Radiation Effects on Animals- Man