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Effects of electron acceptors and radical scavengers on nonchain radical nucleophilic substitution reactions

Journal Article · · Journal of Organic Chemistry; (United States)
DOI:https://doi.org/10.1021/jo00053a040· OSTI ID:6131400

The yields of reaction products from thermal nucleophilic substitution reactions in dimethyl sulfoxide (DMSO) of six o- and p-nitrohalobenzenes with the sodium salt of ethyl [alpha]-cyanoacetate carbanion [Na[sup +][sup [minus]]CH(CN)CO[sub 2]Et] were found to be markedly diminished by addition of small amounts of strong electron acceptors (p-dinitrobenzene, m-dinitrobenzene, and o-dinitrobenzene), but little or no diminished effects on the yields of reaction products were observed by addition of radical scavengers (such as galvinoxyl, nitroxyl, etc.). The results are consistent with the conclusion that these reactions proceed via a nonchain radical nucleophilic substitution mechanism. 28 refs., 3 tabs.

OSTI ID:
6131400
Journal Information:
Journal of Organic Chemistry; (United States), Journal Name: Journal of Organic Chemistry; (United States) Vol. 58:1; ISSN 0022-3263; ISSN JOCEAH
Country of Publication:
United States
Language:
English