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Effectiveness of 1-bromo-3-chloro-5,5-dimethylhydantoin against Legionella pneumophila in a cooling tower

Journal Article · · Appl. Environ. Microbiol.; (United States)
OSTI ID:6109497
Cooling towers are considered to be man-made amplifiers of Legionella spp. Thus, the proper maintenance and choice of biocides is important. The only biocidal measure that has thus far been shown to be effective in field tests is the judicious use of chlorination. Perturbation studies with 1-bromo-3-chloro-5,5-dimethylhydantoin (Bromicide; Great Lakes Chemical Corporation, West Lafayette, Indiana) (BCD) were conducted on an industrial cooling tower shown to contain Legionella pneumophila. At the concentrations recommended by the manufacturer, neither the density nor the activity of L. pneumophila was affected. At concentrations greater than 2l0 ppm (2.0 ..mu..g/ml) free of residual, BCD was not effective in reducing L. pneumophila to source water concentrations, nor was it effective in reducing the 2-p-iodophenyl-3-p-nitrophenyl-5-phenyl tetrazolium chloride activity of the bacterium in situ. The data indicate that at concentrations up to 2.0 ppm, BCD is not effective in these tower studies.
Research Organization:
Savannah River Lab., Aiken, SC
OSTI ID:
6109497
Journal Information:
Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 47:6; ISSN AEMID
Country of Publication:
United States
Language:
English