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U.S. Department of Energy
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Control of nonlinear bioreactor system using a robust multivariable control design methodology

Conference ·
OSTI ID:6104371
This paper describes the simulation results of applying a robust multi-variable control design methodology to a nonlinear bacterial growth system. The modeling for the growth system is through an unstructured modeling approach based on component balance. The model is represented by state-space format with white noises present in both the dynamic as well as the measurement processes. The control objective is to operate the system close to a chosen set point in a stable manner in the presence of external perturbations and internal model uncertainty. The nonlinear system was first linearized around a nominal operating point. Then, the control design methodology of linear-quadratic-Gaussian/loop-transfer-recovery (LQG/LTR) was used in conjunction with an expert system, CASCADE, to arrive at the Kalman-filter and the regulator gains. Computer simulation, using the original nonlinear equations to generate the ''raw'' measurements, showed that the closed-loop system remains stable in the presence of up to 15% variations in the system parameters. This robust controller design approach has strong application potential to industrial systems employing biotechnical processes in the production of foods, pharmaceuticals, and related products.
OSTI ID:
6104371
Report Number(s):
CONF-870323-
Country of Publication:
United States
Language:
English