Occupational risk factors and Alzheimer's disease: a case-control study

Journal Article · Wed Nov 30 23:00:00 EST 1988 · JOM, J. Occup. Med.; (United States)

DOI:https://doi.org/10.1097/00043764-198812000-00010· OSTI ID:6071515

Shalat, S L; Seltzer, B; Baker, Jr, E L

A case-control study was conducted to assess occupational exposure to organic solvents and lead as risk factors for Alzheimer's disease. All case subjects were diagnosed at a Veterans Administration Hospital in Bedford, Massachusetts. Control subjects were selected from Massachusetts voter registration lists and matched by sex, year of birth, and town of residence. Information on occupational history was assessed by mailed questionnaire sent to the spouse or next of kin of the study subject. A total of 98 case and 162 control subjects were included in the matched analysis. No apparent association of increased risk of Alzheimer's disease was observed for ever having occupational exposure to organic solvents or lead.

• Research Organization: Harvard School of Public Health, Boston, MA (USA)
• OSTI ID: 6071515
• Journal Information: JOM, J. Occup. Med.; (United States), Journal Name: JOM, J. Occup. Med.; (United States) Vol. 30:12; ISSN JJOMD
• Country of Publication: United States
• Language: English

Related Subjects

550900 -- Pathology
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
DISEASES
ELEMENTS
EPIDEMIOLOGY
LEAD
MAMMALS
MAN
METALS
NERVOUS SYSTEM DISEASES
OCCUPATIONAL EXPOSURE
ORGANIC SOLVENTS
PRIMATES
RISK ASSESSMENT
SOLVENTS
TOXICITY
VERTEBRATES