Effect of extradural blockage upon glucose and urea kinetics in surgical patients

Journal Article · Tue Sep 01 00:00:00 EDT 1987 · Surg. Gynecol. Obstet.; (United States)

OSTI ID:6071506

Shaw, J H; Galler, L; Holdaway, I M; Holdaway, C M

We have determined the metabolic effects induced by the use of extradural blockage with 0.5 per cent bupivacaine hydrochloride in a group of surgical patients. Turnover rates of glucose and urea were determined isotopically using radioisotopes and studies were performed both in the basal state and during total parenteral nutrition. In the basal state, extradural blockade resulted in a decrease in the turnover rates of both glucose and urea. In addition, when extradural blockade was instituted while the patients were receiving total parenteral nutrition, there was also a significant fall in glucose turnover. We conclude that the use of extradural blockade is effective as a means of conserving bodily resources in surgical patients both in the basal state and during total parenteral nutrition.

• Research Organization: Auckland Hospital, New Zealand
• OSTI ID: 6071506
• Journal Information: Surg. Gynecol. Obstet.; (United States), Vol. 165:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
ANESTHETICS
BIOLOGICAL EFFECTS
GLUCOSE
BIOCHEMICAL REACTION KINETICS
UREA
PATIENTS
PROTEINS
RADIOISOTOPES
SURGERY
TRACER TECHNIQUES
ALDEHYDES
AMIDES
CARBOHYDRATES
CARBONIC ACID DERIVATIVES
CENTRAL NERVOUS SYSTEM DEPRESSANTS
DRUGS
HEXOSES
ISOTOPE APPLICATIONS
ISOTOPES
KINETICS
MEDICINE
MONOSACCHARIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
REACTION KINETICS
SACCHARIDES
550600* - Medicine
550201 - Biochemistry- Tracer Techniques