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Effect of extradural blockage upon glucose and urea kinetics in surgical patients

Journal Article · · Surg. Gynecol. Obstet.; (United States)
OSTI ID:6071506
; ; ;
We have determined the metabolic effects induced by the use of extradural blockage with 0.5 per cent bupivacaine hydrochloride in a group of surgical patients. Turnover rates of glucose and urea were determined isotopically using radioisotopes and studies were performed both in the basal state and during total parenteral nutrition. In the basal state, extradural blockade resulted in a decrease in the turnover rates of both glucose and urea. In addition, when extradural blockade was instituted while the patients were receiving total parenteral nutrition, there was also a significant fall in glucose turnover. We conclude that the use of extradural blockade is effective as a means of conserving bodily resources in surgical patients both in the basal state and during total parenteral nutrition.
Research Organization:
Auckland Hospital, New Zealand
OSTI ID:
6071506
Journal Information:
Surg. Gynecol. Obstet.; (United States), Journal Name: Surg. Gynecol. Obstet.; (United States) Vol. 165:3; ISSN SGOBA
Country of Publication:
United States
Language:
English

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Related Subjects

550201 -- Biochemistry-- Tracer Techniques
550600* -- Medicine
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ALDEHYDES
AMIDES
ANESTHETICS
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
CARBOHYDRATES
CARBONIC ACID DERIVATIVES
CENTRAL NERVOUS SYSTEM DEPRESSANTS
DRUGS
GLUCOSE
HEXOSES
ISOTOPE APPLICATIONS
ISOTOPES
KINETICS
MEDICINE
MONOSACCHARIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PATIENTS
PROTEINS
RADIOISOTOPES
REACTION KINETICS
SACCHARIDES
SURGERY
TRACER TECHNIQUES
UREA