Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Radiation-induced leiomyosarcoma of the great vessels presenting as superior vena cava syndrome

Journal Article · · Cancer (Philadelphia); (United States)
; ; ; ; ; ; ; ; ;
A patient with a pleomorphic intravascular leiomyosarcoma of the great vessels of the neck and mediastinum presented clinically with a superior vena cava syndrome. A latent period of 29 years elapsed between receiving orthovoltage radiation to the neck and right side of chest to treat recurrent ganglioneuroblastoma, and the appearance of a leiomyosarcoma and subsequent recurrences. The patient underwent partial resection of the tumor, received adjunct chemotherapy, and was shown to be free of disease by clinical tests and by magnetic resonance imaging (MRI) 17 months after completion of chemotherapy. The criteria for the diagnosis of radiation-induced sarcomas are reviewed in relation to the present case. The critical role of magnetic resonance imaging in both the diagnosis and continued follow-up of the patient is described. This would appear to be the first reported case of radiation-induced intravascular leiomyosarcoma of the great vessels of the neck and mediastinum presenting as a superior vena cava syndrome.
Research Organization:
Allegheny General Hospital, Pittsburgh, PA
OSTI ID:
6069156
Journal Information:
Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 60:6; ISSN CANCA
Country of Publication:
United States
Language:
English

Similar Records

Radionuclide venography in the evaluation of superior vena cava syndrome
Journal Article · Tue Mar 31 23:00:00 EST 1981 · Clin. Nucl. Med.; (United States) · OSTI ID:5638791
Radionuclide venography in the evaluation of superior vena cava syndrome
Journal Article · Tue Mar 31 23:00:00 EST 1981 · Clin. Nucl. Med.; (United States) · OSTI ID:5681783
Treatment of Superior Vena Cava (SVC) Syndrome and Inferior Vena Cava (IVC) Thrombosis in a Patient with Colorectal Cancer: Combination of SVC Stenting and IVC Filter Placement to Palliate Symptoms and Pave the Way for Port Implantation
Journal Article · Tue Jul 15 00:00:00 EDT 2008 · Cardiovascular and Interventional Radiology · OSTI ID:21467389

Related Subjects

550600 -- Medicine
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEMOTHERAPY
CHEST
DELAYED RADIATION EFFECTS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
MAGNETIC RESONANCE
MEDIASTINUM
MEDICINE
NECK
NEOPLASMS
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
NUCLEAR MEDICINE
PATIENTS
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
RESONANCE
SARCOMAS
SIDE EFFECTS
SURGERY
THERAPY