Radiation necrosis of the optic chiasm, optic tract, hypothalamus, and upper pons after radiotherapy for pituitary adenoma, detected by gadolinium-enhanced, T1-weighted magnetic resonance imaging: Case report

Journal Article · Mon Oct 01 00:00:00 EDT 1990 · Neurosurgery; (USA)

DOI:https://doi.org/10.1227/00006123-199010000-00025· OSTI ID:6067645

Tachibana, O; Yamaguchi, N; Yamashima, T; Yamashita, J ^[1]

---

1. Univ. of Kanazawa School of Medicine (Japan)

A 26-year-old woman was treated for a prolactin secreting pituitary adenoma by surgery and radiotherapy (5860 rads). Fourteen months later, she developed right hemiparesis and dysarthria. A T1-weighted magnetic resonance imaging scan using gadolinium contrast showed a small, enhanced lesion in the upper pons. Seven months later, she had a sudden onset of loss of vision, and radiation optic neuropathy was diagnosed. A T1-weighted magnetic resonance imaging scan showed widespread gadolinium-enhanced lesions in the optic chiasm, optic tract, and hypothalamus. Magnetic resonance imaging is indispensable for the early diagnosis of radiation necrosis, which is not visualized by radiography or computed tomography.

• OSTI ID: 6067645
• Journal Information: Neurosurgery; (USA), Vol. 27:4; ISSN 0148-396X
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
RADIOTHERAPY
HYPOTHALAMUS
BIOLOGICAL RADIATION EFFECTS
PITUITARY GLAND
RADIATION INJURIES
DIAGNOSIS
SIDE EFFECTS
GADOLINIUM ISOTOPES
NMR IMAGING
BIOLOGICAL EFFECTS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
INJURIES
ISOTOPES
MEDICINE
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
RARE EARTH ISOTOPES
THERAPY
560151* - Radiation Effects on Animals- Man
550601 - Medicine- Unsealed Radionuclides in Diagnostics