recA and catalase in H sub 2 O sub 2 -mediated toxicity in Neisseria gonorrhoeae

Journal Article · Sat Dec 01 00:00:00 EST 1990 · Journal of Bacteriology; (USA)

OSTI ID:6065456

Hassett, D J; Charniga, L; Cohen, M S ^[1]

---

1. Univ. of North Carolina, Chapel Hill (USA)

Neisseria gonorrhoeae cells defective in the biosynthesis of the recA gene product are no more sensitive to hydrogen peroxide than wild-type cells. Although gonococci possess nearly 100-fold-greater catalase levels than Escherichia coli, they are more susceptible to hydrogen peroxide than this organism. The natural niche of gonococci undoubtedly results in exposure to oxidant stress; however, they do not demonstrate particularly efficient antioxidant defense systems.

• OSTI ID: 6065456
• Journal Information: Journal of Bacteriology; (USA), Vol. 172:12; ISSN 0021-9193
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
SENSITIVITY
HYDROGEN PEROXIDE
TOXICITY
CATALASE
DNA REPAIR
GENES
GONORRHEA
MUTATIONS
BACTERIAL DISEASES
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
DISEASES
ENZYMES
HYDROGEN COMPOUNDS
INFECTIOUS DISEASES
MICROORGANISMS
OXIDOREDUCTASES
OXYGEN COMPOUNDS
PEROXIDASES
PEROXIDES
RECOVERY
REPAIR
UROGENITAL SYSTEM DISEASES
560300* - Chemicals Metabolism & Toxicology