Impact of an isotopic effect on the interpretation of bioassay data for Pu

Journal Article · Tue Sep 01 04:00:00 EDT 1987 · Health Phys.; (United States)

DOI:https://doi.org/10.1097/00004032-198709000-00004· OSTI ID:6063296

Ryan, M T; Poston, J W

A review of the aggregate recoil phenomenon and its potential influence on transfer rates of /sup 238/PuO/sub 2/ and /sup 239/PuO/sub 2/ across the human alveolar wall indicated a significant difference between these two isotopic compounds. Transfer rates were determined in in vitro experiments and the ratio of the transfer rates for /sup 238/Pu to /sup 239/Pu was approximately 140 (Ry82). Calculations were performed to assess the importance of this finding on the internal dosimetry of insoluble /sup 238/Pu, using methods and models recommended by the International Commission on Radiological Protection (ICRP). It was found that the committed dose equivalent per unit intake was not influenced by the transfer rate from the pulmonary compartment to blood.

• Research Organization: Chem-Nuclear Systems, Inc., Barnwell, SC
• OSTI ID: 6063296
• Journal Information: Health Phys.; (United States), Journal Name: Health Phys.; (United States) Vol. 53:3; ISSN HLTPA
• Country of Publication: United States
• Language: English

Related Subjects

560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ANIMALS
BIOASSAY
BODY
BODY BURDEN
DOCUMENT TYPES
DOSE EQUIVALENTS
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
HEAVY NUCLEI
INHALATION
INTAKE
ISOTOPE EFFECTS
ISOTOPES
LUNGS
MAMMALS
MAN
MEMBRANE TRANSPORT
NUCLEI
ORGANS
PLUTONIUM 238
PLUTONIUM 239
PLUTONIUM ISOTOPES
PRIMATES
RADIOISOTOPES
RADIONUCLIDE KINETICS
RESPIRATORY SYSTEM
REVIEWS
VERTEBRATES
YEARS LIVING RADIOISOTOPES