Detection of gastrointestinal blood loss with 99mTc-labeled, heat-treated red blood cells. [Dogs]
Journal Article
·
· Radiology; (United States)
OSTI ID:6062820
Studies in dogs showed that heat-treated 99mTc-labeled red blood cells (HT/RBC) afford a highly sensitive means of detecting gastrointetinal bleeding as low as 0.12 ml/min., which could not be seen with unheated 99mTc-RBC, 99mTc-sulfur colloid, or 99mTc-DTPA. In addition, as the right upper quadrant and epigastrium remained free of activity, only one fifth to one tenth of the dose of 99mTc was needed. The safety of HT/RBC in humans has been documented, and the experiments in dogs suggest that it may have advantages over other agents in detecting gastrointestinal bleeding.
- OSTI ID:
- 6062820
- Journal Information:
- Radiology; (United States), Journal Name: Radiology; (United States) Vol. 138:1; ISSN RADLA
- Country of Publication:
- United States
- Language:
- English
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· AJR, Am. J. Roentgenol.; (United States)
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Tue Mar 31 23:00:00 EST 1987
· J. Nucl. Med.; (United States)
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
BODY TEMPERATURE
COUNTING TECHNIQUES
DIAGNOSIS
DIGESTIVE SYSTEM
DOGS
DOSES
ERYTHROCYTES
GASTROINTESTINAL TRACT
HEMORRHAGE
HOURS LIVING RADIOISOTOPES
HYPERTHERMIA
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
RADIATION DOSES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
BODY TEMPERATURE
COUNTING TECHNIQUES
DIAGNOSIS
DIGESTIVE SYSTEM
DOGS
DOSES
ERYTHROCYTES
GASTROINTESTINAL TRACT
HEMORRHAGE
HOURS LIVING RADIOISOTOPES
HYPERTHERMIA
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
RADIATION DOSES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES