Hematology of mercury toxicity in young chickens

Journal Article · Tue Jan 01 04:00:00 EST 1974 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01713025· OSTI ID:6062135

Thaxton, P; Young, P S; Cogburn, L A; Parkhurst, C R

Chickens were administered mercury as mercuric chloride during their juvenile development. Significantly lower body weights were found at 2, 4 and 6 weeks in the chicks which received Hg at the level of 300 ppm. The body weights of the birds which received 150 ppm of Hg were lower at each of the bi-weekly periods; however, these differences were not significant. 300 ppm of Hg caused an increase in packed cell volume (PCV) at all times of measurement. The lower dose of 150 ppm did not significantly affect the PCV at 2 or 4 weeks, but did cause increased PCV at 6 weeks of age. At the dose rate of 300 ppm, significantly greater numbers of erythrocytes were found throughout the experimental period. Erythrocyte numbers of the 150 ppm birds did not differ from the controls at 2 or 4 weeks; however, these birds did have significantly less erythrocytes at 6 weeks of age. 300 ppm of Hg resulted in decreased numbers of leucocytes. 150 ppm resulted in decreased leucocytes at 2 and 4 weeks of age, but not at 6 weeks of age. Both 150 and 300 ppm resulted in significantly fewer circulating lymphocytes at 4 and 6 weeks. 18 references, 6 figures.

• Research Organization: North Carolina State Univ., Raleigh
• OSTI ID: 6062135
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 12:1; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMAL GROWTH
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIRDS
BLOOD
BLOOD CELLS
BLOOD COUNT
BODY FLUIDS
CHICKENS
CHLORIDES
CHLORINE COMPOUNDS
CONNECTIVE TISSUE CELLS
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
ERYTHROCYTES
FOWL
GROWTH
HALIDES
HALOGEN COMPOUNDS
INHIBITION
LEUKOCYTES
LYMPHOCYTES
MATERIALS
MERCURY
MERCURY CHLORIDES
MERCURY COMPOUNDS
MERCURY HALIDES
METALS
PATHOLOGICAL CHANGES
SOMATIC CELLS
TOXICITY
VERTEBRATES