Long-term follow-up in toxic solitary autonomous thyroid nodules treated with radioactive iodine
Journal Article
·
· Journal of Nuclear Medicine; (USA)
OSTI ID:6059074
- University Hospital Nijmegen (Netherlands)
The long-term effects of radioiodine treatment on thyroid function in patients with a toxic solitary autonomous thyroid nodule were evaluated. Fifty-two patients received a therapeutic dose of 20 mCi of iodine-131 ({sup 131}I). Duration of follow-up was 10 +/- 4 yr. Follow-up data included a biochemical evaluation of thyroid function. The failure rate (recurrent hyperthyroidism) was 2%. The incidence of hypothyroidism was 6% and was not related to the dose per gram of nodular tissue. Oral administration of 20 mCi of radioiodine is a simple and highly effective method for the treatment of patients with a toxic autonomous thyroid nodule. The risk of development of hypothyroidism is low if extranodular uptake of {sup 131}I is prevented. This can be achieved by not treating euthyroid patients, by no longer using injections of exogenous thyroid stimulating hormone in the diagnostic work-up of the patients and by always performing radioiodine imaging shortly before treatment.
- OSTI ID:
- 6059074
- Journal Information:
- Journal of Nuclear Medicine; (USA), Journal Name: Journal of Nuclear Medicine; (USA) Vol. 32:1; ISSN 0161-5505; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Follow-up of solitary autonomous thyroid nodules treated with /sup 131/I
Solitary autonomous thyroid nodules: comparison of fluorescent and pertechnetate imaging. [/sup 99m/Tc tracer technique]
Successful treatment of solitary toxic thyroid nodules with relatively low-dose iodine-131, with low prevalence of hypothyroidism
Journal Article
·
Wed Dec 14 23:00:00 EST 1983
· N.Engl. J. Med.; (United States)
·
OSTI ID:7013000
Solitary autonomous thyroid nodules: comparison of fluorescent and pertechnetate imaging. [/sup 99m/Tc tracer technique]
Journal Article
·
Mon Oct 31 23:00:00 EST 1977
· J. Nucl. Med.; (United States)
·
OSTI ID:5436588
Successful treatment of solitary toxic thyroid nodules with relatively low-dose iodine-131, with low prevalence of hypothyroidism
Journal Article
·
Mon Oct 01 00:00:00 EDT 1984
· Ann. Intern. Med.; (United States)
·
OSTI ID:6334474
Related Subjects
550604* -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
HYPOTHYROIDISM
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOTOPES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORAL ADMINISTRATION
ORGANS
PATIENTS
POST-IRRADIATION EXAMINATION
RADIATION DOSES
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY
THYROID
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
HYPOTHYROIDISM
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOTOPES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORAL ADMINISTRATION
ORGANS
PATIENTS
POST-IRRADIATION EXAMINATION
RADIATION DOSES
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY
THYROID