Comparison of metabolic rates, language, and memory in subcortical aphasias. [Tomographic studies using /sup 18/F-fluorodeoxyglulcose]
Four patients with subcortical lesions and either aphasia or amnesia were compared to four patients with cortical lesions and aphasia. Each patient had /sup 18/F-fluorodeoxyglucose positron emission computed tomography and language and memory evaluations. Metabolic depression was found in the thalamus and caudate in both groups, while only the cortical group showed cortical changes. Language changes were mild in the subcortical, while moderate to severe in the cortical group. Both groups showed severe verbal memory dysfunction. The only common abnormalities in the two groups were metabolic changes in thalamus, and severity of verbal memory dysfunction. These findings suggest a relationship between verbal memory and thalamic function.
- Research Organization:
- California Univ., Los Angeles (USA)
- DOE Contract Number:
- AC03-76SF00012
- OSTI ID:
- 6058388
- Report Number(s):
- UCLA-12-1318; CONF-8104116-1; ON: DE82001094
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BEHAVIOR
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CEREBRAL CORTEX
CEREBRUM
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
EMISSION COMPUTED TOMOGRAPHY
FLUORINE 18
FLUORINE ISOTOPES
HOURS LIVING RADIOISOTOPES
INJURIES
ISOTOPES
LIGHT NUCLEI
METABOLISM
NERVOUS SYSTEM
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC FLUORINE COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
THALAMUS
TOMOGRAPHY