Comparison of the barium test meal and the gamma camera scanning technic in measuring gastric emptying
In 21 patients with nonresected stomachs and symptoms of delayed gastric emptying, obstruction was excluded by upper gastrointestinal series and upper endoscopy; all had abnormal results of barium test meal (BTM) study. Each had repeat BTM after the administration of 10 mg of metoclopramide. Each patient also had two gamma camera studies after a technetium Tc 99m sulfur colloid labeled meal; normal saline or metoclopramide was administered before each test in a blinded and random manner. Half-time (T 1/2) and percentage of isotope remaining at six hours (GC6) were recorded. Ten asymptomatic controls had a gamma camera scanning study, and seven of these had a BTM. Nine of 19 patients had a T 1/2 in the normal range, and in 12 of 19 patients the GC6 was in the normal range. The magnitude of retention of barium at six hours on the BTM did not correlate with the T 1/2 (r = 0.076) or the GC6 (r = 0.296). Thus, these tests were not comparable in this study. By regression analysis, a significant reduction was shown in the amount of retained food and barium (P < .01), the T 1/2 (P < .01), and the GC6 (P < .01) after intramuscular administration of metoclopramide, indicating that both tests were able to evaluate the effects of this drug.
- Research Organization:
- Emory Univ. School of Medicine, Atlanta, GA
- OSTI ID:
- 6058365
- Journal Information:
- South. Med. J.; (United States), Vol. 74:9
- Country of Publication:
- United States
- Language:
- English
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DIAGNOSTIC TECHNIQUES
COMPARATIVE EVALUATIONS
GASTROINTESTINAL TRACT
BARIUM
COLLOIDS
DRUGS
GAMMA CAMERAS
ISOMERS
MEDICINE
PATIENTS
RADIOISOTOPE SCANNERS
REGRESSION ANALYSIS
TECHNETIUM 99
ALKALINE EARTH METALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CAMERAS
DIGESTIVE SYSTEM
DISPERSIONS
ELEMENTS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATHEMATICS
METALS
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPES
STATISTICS
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics